标题: 嵌合抗原受体T细胞在恶性血液疾病中的治疗 [打印本页] 作者: icartab 时间: 2016-2-17 18:50 标题: 嵌合抗原受体T细胞在恶性血液疾病中的治疗 技术资料下载地址: http://www.ncbi.nlm.nih.gov/pubmed/26874466
文献来源： Transfus Apher Sci
Chimeric antigen receptor T cell treatment in hematologic malignancies.
Abstract
Adoptive transfer of T cells that have genetically engineered chimeric antigen receptors (CARs) is an encouraging treatment modality in the hematological malignancies. These T cells are capable of selectively recognizing tumor-associated antigens. There are a variety of reported, as well as ongoing studies on the utilization of CAR-T cells in the treatment of leukemia, myeloma, as well as B and T cell lymphomas. In this review, we aimed to highlight current understanding of this promising treatment modality, including its efficacy and adverse effects.