此研究得到国家自然科学基金委员会国家杰出青年科学基金项目（81525023）的资助。研究结果以“Global epidemiology of avian influenza A H5N1 virus infection in humans, 1997–2015: a systematic review of individual case data” 为题发表在国际著名医学期刊Lancet Infectious Diseases (IF 22.4)，余宏杰是该论文的通讯作者。（论文链接：http://www.thelancet.com/pdfs/journals/laninf/PIIS1473-3099(16)00153-5.pdf）。
Global epidemiology of avian influenza A H5N1 virus infection in humans, 1997–2015: a systematic review of individual case data
【Summary】Avian infl uenza A H5N1 viruses have caused many, typically severe, human infections since the fi rst human case was reported in 1997. However, no comprehensive epidemiological analysis of global human cases of H5N1 from 1997 to 2015 exists. Moreover, few studies have examined in detail the changing epidemiology of human H5N1 cases in Egypt, especially given the outbreaks since November, 2014, which have the highest number of cases ever reported worldwide in a similar period. Data on individual patients were collated from diff erent sources using a systematic approach to describe the global epidemiology of 907 human H5N1 cases between May, 1997, and April, 2015. The number of aff ected countries rose between 2003 and 2008, with expansion from east and southeast Asia, then to west Asia and Africa. Most cases (67·2%) occurred from December to March, and the overall case-fatality risk was 483 (53·5%) of 903 cases which varied across geographical regions. Although the incidence in Egypt has increased dramatically since November, 2014, compared with the cases beforehand, there were no signifi cant diff erences in the fatality risk, history of exposure to poultry, history of patient contact, and time from onset to hospital admission in the recent cases.