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Brown, Gordon D.; Netea, Mihai G. (Eds.)
2007, XVIII, 492 p.
The immunology of fungal infections is a comprehensive text covering all aspects of the immunology of infection with these pathogens. In addition to established knowledge, this book covers recent developments in the innate and adaptive immunological mechanisms involved in the host response to fungal infection.
The volume is divided into a number of sections, which provides an immunological perspective on the cells, soluble factors and receptors involved in recognising and combating infections with these organisms. Further sections provide detailed descriptions of immunity to specific fungal pathogens, immune-escape mechanisms used by fungi and immune-based therapeutic strategies.
This book will be a valuable resource for those interested in fungal immunology particularly, students, specialists, teachers, researchers and clinicians.
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Section 1: Cells
chapter 1: Macrophages
Sigrid E.M. Heinsbroek and Siamon Gordon; University of Oxford
chapter 2: Dendritic cells
Luigina Romani; University of Perugia
chapter 3: The neutrophil
David H. Dockrell, Emmet E. McGrath, Moira KB Whyte, and Ian Sabroe; University of Sheffield
chapter 4: Lymphocytes
Anna Vecchiarelli, Antonella Mencacci, Francesco Bistoni ; University of Perugia
chapter 5: Other cells: The role of non-neutrophilic granulocytes, NK and NKT cells in fungal immunology
Jeremy CD Wiseman and Christopher H. Mody; University of Calgary
chapter 6: Genes and gene pathways in Candida Infection
Robert B. Ashman, Camile S. Fara, and Christine Wells; University of Queensland and Griffith University
Section 2: Soluble factors
chapter 7: Collectins and pentraxins
Uday Kishore and Ken Reid; University of Oxford and Justus-Liebig-University
chapter 8: Complement in fungal infections and complement evasion strategies
Cornelia Speth, Cornelia Lass-Flörl and Reinhard Würzner; Innsbruck Medical University and Ludwig-Boltzmann-Institute of AIDS Research.
chapter 9: Cytokines
Karen F. Buckland and Cory M. Hogaboam; University of Michigan Medical School.
chapter 10: Antibodies
Josè Lòpez-Ribot, Rosalìa Dìez-Orejas and Concha Gil ; The University of Texas at San Antonio and Complutense University
Section 3: Non-Opsonic Fungal Receptors
chapter 11: The recognition of fungal pathogens by Toll-like receptors
Mihai G. Netea, Jos WM Van der Meer, Bart Jan Kullberg; Radboud University Nijmegen Medical Center and Nijmegen University Center for Infectious Diseases
chapter 12: Fungal ß-glucans and their receptors
S Vicky Tsoni and Gordon D Brown; University of Cape Town
chapter 13: Detection of fungi by mannose-based recognition receptors
F Meyer-Wentrup, A Cambi, CG Figdor and GJ Adema; Radboud University Nijmegen Medical Center
Section 4: Immunity to specific pathogens
chapter 14: Pneumocystis
Laura McKinley and Chad Steele, University of Pittsburgh School of Medicine
chapter 15: Interactions of Aspergillus fumigatus with its host during invasive pulmonary infections
Jean-Paul Latgé and Anne Beauvais; Pasteur Institute
chapter 16: C. albicans and C. glabrata
Desa Lilic and Ken Haynes, School of Clinial Medicines, Newcastle University and Department of INfectious diseases, Imerpial College London
chapter 17: Immunology of infections with Cryptococcus neoformans
Pauline Ellerbroek, Anna Vecchiarelli, Andy Hoepelman and Frank Coenjaerts; University Medical Center and University of Perugia.
chapter 18: Histoplasma capsulatum
Joshua D Nosanchuk; Albert Einstein College of Medicine
Section 5
chapter 19: Escape mechanisms from the immune response
David M. Underhill; Cedars-Sinai Medical Center
Section 6: Immune-based therapeutic strategies
chapter 20: Cytokine treatment of fungal infections
Bart-Jan Kullberg; Radboud University Nijmegen Medical Center
chapter 21: Fungal vaccines and vaccination: problems and perspectives
Antonio Cassone; Istituto Superiore di Santià