, `" Q0 ]0 W, l8 HThe book gives a comprehensive overview on the knowledge of virus infection relevant for humans and animals. For each virus family the molecular details of the virus particle and the viral replication cycle are described. In the case of virus types with relevance for human and/or animal health the data on molecular biology, genetics and virus-cell interaction are combined with those concerning, pathogenesis, epidemiology, clinics, prevention and therapy. 3 W! a+ v0 h" {( V& v5 O% |) q9 b' c
作者简介) z) Q& ~+ Q6 ^! @' }% z
Susanne Modrow is professor of genetics at the Institute for Medical Microbiology and Hygiene at the University of Regensburg, where she also directs a research department for molecular virology.2 {- K n. Q. Y+ H- y
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Dietrich Falke is Professor Emeritus at the Institute for Virology at the Johannes Gutenberg University in Mainz., g: I+ |+ i# ~
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Uwe Truyen is professor of animal hygiene and control of epizootic disease. He is head of the Institute of Animal Hygiene and Veterinary Public Health in the Centre of Veterinary Public Health of the University Leipzig, Germany. " e0 y8 }6 G) v7 Q/ i% q5 Z$ R* }: r2 c" C
Hermann Schätzl was professor of clinical virology at the Institute for Virology at the Technical University Munich and is now Wyoming Excellence Chair and professor at the University of Wyoming, departments of veterinary sciences and molecular biology. ' J3 e8 J! N) r( S7 C
" g1 f" w9 Q: V& M目录. | r: n/ u) W
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A General part9 F0 l, @! N. |) I. U$ K0 a9 f
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Historical overview.- Viruses: definition, structure, classification.- Virus proliferation and replication.- Pathogenesis.- Cell damage.- Transformation and carcinogenesis.-Immunology.- Cytokines, chemokines and interferons.- Chemotherapy.- Vaccines.- Epidemiology.- Virus evolution.- Laboratory methods for detection virus infections - @9 g ^3 P" t8 A6 c$ j & k& @$ m" f) |0 D% b5 \
8 r/ b8 _1 x: v3 E, UB Special part0 J! K) A' S( v; a* t# o
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Viruses with single-stranded, positive-sense RNA genomes.- Viruses with single-stranded, non-segmented, negative-sense RNA genomes.- Viruses with single-stranded, segmented, negative-sense RNA genomes.- Viruses with double-stranded, segmented RNA genomes.- Viruses with single-stranded RNA genomes and double stranded DNA as intermediate products.- Viruses with a double-stranded DNA genome.- Viruses with a single-stranded DNA genome.- Prions.- Appendix 1: Transmission electron microscopy in virology: principles, preparation methods and rapid diagnosis.- Appendix 2: Information on the "prototypical electron microscopic portraits" of individual virus families.-Glossary3 Z5 @, K+ H H$ a4 C: f9 e