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[size=1.1em]Spotlight
[size=1.2em]Articles of Significant Interest Selected from This Issue by the Editors
J. Virol. July 2016 90:6173; doi:10.1128/JVI.00964-16[size=0.9em] FREE
http://jvi.asm.org/content/90/14/6173
[size=1.1em]Structure and Assembly
[size=1.2em]A Single Amino Acid Substitution in Poliovirus Nonstructural Protein 2CATPase Causes Conditional Defects in Encapsidation and Uncoating
[size=1em]Emmanuel Asare, JoAnn Mugavero, Ping Jiang, Eckard Wimmer, and Aniko V. Paul
J. Virol. July 2016 90:6174-6186; Accepted manuscript posted online 13 April 2016, doi:10.1128/JVI.02877-15 [size=0.9em]OPEN ACCESS
http://jvi.asm.org/content/90/14/6174.abstract
[size=1.2em]Membrane Anchors of the Structural Flavivirus Proteins and Their Role in Virus Assembly
[size=1em]Janja Blazevic, Harald Rouha, Victoria Bradt, Franz X. Heinz, and Karin Stiasny
[size=1em]J. Virol. July 2016 90:6365-6378; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00447-16
http://jvi.asm.org/content/90/14/6365.abstract
[size=1.2em]In Vivo Analysis of Infectivity, Fusogenicity, and Incorporation of a Mutagenic Viral Glycoprotein Library Reveals Determinants for Virus Incorporation
[size=1em]Daniel J. Salamango, Khalid K. Alam, Donald H. Burke, and Marc C. Johnson
J. Virol. July 2016 90:6502-6514; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00804-16[size=0.9em] SPOTLIGHT
http://jvi.asm.org/content/90/14/6502.abstract
[size=1.1em]Genome Replication and Regulation of Viral Gene Expression
[size=1.2em]Functional Regulation of an Autographa californica Nucleopolyhedrovirus-Encoded MicroRNA, AcMNPV-miR-1, in Baculovirus Replication
[size=1em]Mengxiao Zhu, Jinwen Wang, Riqiang Deng, and Xunzhang Wang
[size=1em]J. Virol. July 2016 90:6526-6537; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00165-16
http://jvi.asm.org/content/90/14/6526.abstract
[size=1.1em]Genetic Diversity and Evolution
[size=1.2em]Unexpected Interfarm Transmission Dynamics during a Highly Pathogenic Avian Influenza Epidemic
[size=1em]Alice Fusaro, Luca Tassoni, Adelaide Milani, Joseph Hughes, Annalisa Salviato, Pablo R. Murcia, Paola Massi, Gianpiero Zamperin, Lebana Bonfanti, Stefano Marangon, Giovanni Cattoli, and Isabella Monne
[size=1em]J. Virol. July 2016 90:6401-6411; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00538-16
http://jvi.asm.org/content/90/14/6401.abstract
[size=1.1em]Virus-Cell Interactions
[size=1.2em]Furin Cleavage of L2 during Papillomavirus Infection: Minimal Dependence on Cyclophilins
[size=1em]Matthew P. Bronnimann, Christine M. Calton, Samantha F. Chiquette, Shuaizhi Li, Mingfeng Lu, Janice A. Chapman, Kristin N. Bratton, Angela M. Schlegel, and Samuel K. Campos
[size=1em]J. Virol. July 2016 90:6224-6234; Accepted manuscript posted online 27 April 2016, doi:10.1128/JVI.00038-16
http://jvi.asm.org/content/90/14/6224.abstract
[size=1.2em]Colony-Stimulating Factor 1 Receptor Antagonists Sensitize Human Immunodeficiency Virus Type 1-Infected Macrophages to TRAIL-Mediated Killing
[size=1em]Francesc Cunyat, Jennifer N. Rainho, Brian West, Louise Swainson, Joseph M. McCune, and Mario Stevenson
[size=1em]J. Virol. July 2016 90:6255-6262; Accepted manuscript posted online 27 April 2016, doi:10.1128/JVI.00231-16
http://jvi.asm.org/content/90/14/6255.abstract
[size=1.2em]Robust Lys63-Linked Ubiquitination of RIG-I Promotes Cytokine Eruption in Early Influenza B Virus Infection
[size=1em]Jingwen Jiang, Jing Li, Wenhui Fan, Weinan Zheng, Meng Yu, Can Chen, Lei Sun, Yuhai Bi, Chan Ding, George F. Gao, and Wenjun Liu
[size=1em]J. Virol. July 2016 90:6263-6275; Accepted manuscript posted online 27 April 2016, doi:10.1128/JVI.00549-16
http://jvi.asm.org/content/90/14/6263.abstract
[size=1.2em]Calcium-Dependent Rubella Virus Fusion Occurs in Early Endosomes
[size=1em]Mathieu Dubé, Loïc Etienne, Maximilian Fels, and Margaret Kielian
[size=1em]J. Virol. July 2016 90:6303-6313; Accepted manuscript posted online 27 April 2016, doi:10.1128/JVI.00634-16
http://jvi.asm.org/content/90/14/6303.abstract
[size=1.2em]Hepatitis C Virus-Induced Upregulation of MicroRNA miR-146a-5p in Hepatocytes Promotes Viral Infection and Deregulates Metabolic Pathways Associated with Liver Disease Pathogenesis
[size=1em]Simonetta Bandiera, Sophie Pernot, Hussein El Saghire, Sarah C. Durand, Christine Thumann, Emilie Crouchet, Tao Ye, Isabel Fofana, Marine A. Oudot, Jochen Barths, Catherine Schuster, Patrick Pessaux, Markus H. Heim, Thomas F. Baumert, and Mirjam B. Zeisel
[size=1em]J. Virol. July 2016 90:6387-6400; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00619-16
http://jvi.asm.org/content/90/14/6387.abstract
[size=1.2em]Lassa Virus Cell Entry via Dystroglycan Involves an Unusual Pathway of Macropinocytosis
[size=1em]Joel Oppliger, Giulia Torriani, Antonio Herrador, and Stefan Kunz
[size=1em]J. Virol. July 2016 90:6412-6429; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00257-16
http://jvi.asm.org/content/90/14/6412.abstract
[size=1.2em]Tetraspanin CD151 Promotes Initial Events in Human Cytomegalovirus Infection
[size=1em]Daniel Hochdorfer, Luise Florin, Christian Sinzger, and Diana Lieber
J. Virol. July 2016 90:6430-6442; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00145-16[size=0.9em] SPOTLIGHT
http://jvi.asm.org/content/90/14/6430.abstract
[size=1.2em]NF-κB Signaling Regulates Expression of Epstein-Barr Virus BART MicroRNAs and Long Noncoding RNAs in Nasopharyngeal Carcinoma
[size=1em]Rob J. A. Verhoeven, Shuang Tong, Gaohong Zhang, Jingfeng Zong, Yixin Chen, Dong-Yan Jin, Mei-Ru Chen, Jianji Pan, and Honglin Chen
J. Virol. July 2016 90:6475-6488; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00613-16 [size=0.9em]OPEN ACCESS
http://jvi.asm.org/content/90/14/6475.abstract
[size=1.2em]Suppression of Kaposi's Sarcoma-Associated Herpesvirus Infection and Replication by 5′-AMP-Activated Protein Kinase
[size=1em]Fan Cheng, Meilan He, Jae U. Jung, Chun Lu, and Shou-Jiang Gao
[size=1em]J. Virol. July 2016 90:6515-6525; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00624-16
http://jvi.asm.org/content/90/14/6515.abstract
[size=1.2em]Bat Severe Acute Respiratory Syndrome-Like Coronavirus WIV1 Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response
[size=1em]Lei-Ping Zeng, Yu-Tao Gao, Xing-Yi Ge, Qian Zhang, Cheng Peng, Xing-Lou Yang, Bing Tan, Jing Chen, Aleksei A. Chmura, Peter Daszak, and Zheng-Li Shi
[size=1em]J. Virol. July 2016 90:6573-6582; Accepted manuscript posted online 11 May 2016, doi:10.1128/JVI.03079-15
http://jvi.asm.org/content/90/14/6573.abstract
[size=1.2em]HIV-1 Gag, Envelope, and Extracellular Determinants Cooperate To Regulate the Stability and Turnover of Virological Synapses
[size=1em]Jaye C. Gardiner, Eric J. Mauer, and Nathan M. Sherer
[size=1em]J. Virol. July 2016 90:6583-6597; Accepted manuscript posted online 11 May 2016, doi:10.1128/JVI.00600-16
http://jvi.asm.org/content/90/14/6583.abstract
[size=1.2em]MxA Mediates SUMO-Induced Resistance to Vesicular Stomatitis Virus
[size=1em]Ghizlane Maarifi, Zara Hannoun, Marie Claude Geoffroy, Faten El Asmi, Karima Zarrouk, Sébastien Nisole, Danielle Blondel, and Mounira K. Chelbi-Alix
[size=1em]J. Virol. July 2016 90:6598-6610; Accepted manuscript posted online 11 May 2016, doi:10.1128/JVI.00722-16
http://jvi.asm.org/content/90/14/6598.abstract
[size=1.1em]Cellular Response to Infection
[size=1.2em]Hepatitis B Virus Surface Antigen Activates Myeloid Dendritic Cells via a Soluble CD14-Dependent Mechanism
[size=1em]Nadine van Montfoort, Evelyn van der Aa, Aniek van den Bosch, Hilde Brouwers, Thomas Vanwolleghem, Harry L. A. Janssen, Hassan Javanbakht, Sonja I. Buschow, and Andrea M. Woltman
[size=1em]J. Virol. July 2016 90:6187-6199; Accepted manuscript posted online 20 April 2016, doi:10.1128/JVI.02903-15
http://jvi.asm.org/content/90/14/6187.abstract
[size=1.2em]Functional Upregulation of the DNA Cytosine Deaminase APOBEC3B by Polyomaviruses
[size=1em]Brandy Verhalen, Gabriel J. Starrett, Reuben S. Harris, and Mengxi Jiang
[size=1em]J. Virol. July 2016 90:6379-6386; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00771-16
http://jvi.asm.org/content/90/14/6379.abstract
[size=1.2em]Human Cytomegalovirus Induces an Atypical Activation of Akt To Stimulate the Survival of Short-Lived Monocytes
[size=1em]Olesea Cojohari, Megan A. Peppenelli, and Gary C. Chan
[size=1em]J. Virol. July 2016 90:6443-6452; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00214-16
http://jvi.asm.org/content/90/14/6443.abstract
[size=1.2em]Identification of Respiratory Syncytial Virus Nonstructural Protein 2 Residues Essential for Exploitation of the Host Ubiquitin System and Inhibition of Innate Immune Responses
[size=1em]Jillian N. Whelan, Kim C. Tran, Damian B. van Rossum, and Michael N. Teng
[size=1em]J. Virol. July 2016 90:6453-6463; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00423-16
http://jvi.asm.org/content/90/14/6453.abstract
[size=1.2em]Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage
[size=1em]Majid N. Humoud, Nicole Doyle, Elizabeth Royall, Margaret M. Willcocks, Frederic Sorgeloos, Frank van Kuppeveld, Lisa O. Roberts, Ian G. Goodfellow, Martijn A. Langereis, and Nicolas Locker
J. Virol. July 2016 90:6489-6501; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00647-16 [size=0.9em]OPEN ACCESS
http://jvi.asm.org/content/90/14/6489.abstract
[size=1.1em]Prions
[size=1.2em]Analysis of Conformational Stability of Abnormal Prion Protein Aggregates across the Spectrum of Creutzfeldt-Jakob Disease Prions
[size=1em]Maura Cescatti, Daniela Saverioni, Sabina Capellari, Fabrizio Tagliavini, Tetsuyuki Kitamoto, James Ironside, Armin Giese, and Piero Parchi
[size=1em]J. Virol. July 2016 90:6244-6254; Accepted manuscript posted online 27 April 2016, doi:10.1128/JVI.00144-16
http://jvi.asm.org/content/90/14/6244.abstract
[size=1.1em]Vaccines and Antiviral Agents
[size=1.2em]Rearrangement of Influenza Virus Spliced Segments for the Development of Live-Attenuated Vaccines
[size=1em]Aitor Nogales, Marta L. DeDiego, David J. Topham, and Luis Martínez-Sobrido
[size=1em]J. Virol. July 2016 90:6291-6302; Accepted manuscript posted online 27 April 2016, doi:10.1128/JVI.00410-16
http://jvi.asm.org/content/90/14/6291.abstract
[size=1.2em]Broad Cross-Protection Is Induced in Preclinical Models by a Human Papillomavirus Vaccine Composed of L1/L2 Chimeric Virus-Like Particles
[size=1em]Mathieu Boxus, Michel Fochesato, Agnès Miseur, Emmanuel Mertens, Najoua Dendouga, Sarah Brendle, Karla K. Balogh, Neil D. Christensen, and Sandra L. Giannini
J. Virol. July 2016 90:6314-6325; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00449-16[size=0.9em] SPOTLIGHT
http://jvi.asm.org/content/90/14/6314.abstract
[size=1.2em]Association between Hemagglutinin Stem-Reactive Antibodies and Influenza A/H1N1 Virus Infection during the 2009 Pandemic
[size=1em]Le Nguyen Minh Hoa, Le Quynh Mai, Juliet E. Bryant, Pham Quang Thai, Nguyen Le Khanh Hang, Nguyen Thi Thu Yen, Tran Nhu Duong, Dang Dinh Thoang, Peter Horby, Heiman F. L. Werheim, and Annette Fox
J. Virol. July 2016 90:6549-6556; Accepted manuscript posted online 11 May 2016, doi:10.1128/JVI.00093-16 [size=0.9em]OPEN ACCESS
http://jvi.asm.org/content/90/14/6549.abstract
[size=1.1em]Pathogenesis and Immunity
[size=1.2em]Depletion of Alveolar Macrophages Does Not Prevent Hantavirus Disease Pathogenesis in Golden Syrian Hamsters
[size=1em]Christopher D. Hammerbeck, Rebecca L. Brocato, Todd M. Bell, Christopher W. Schellhase, Steven R. Mraz, Laurie A. Queen, and Jay W. Hooper
J. Virol. July 2016 90:6200-6215; Accepted manuscript posted online 20 April 2016, doi:10.1128/JVI.00304-16 [size=0.9em]OPEN ACCESS
http://jvi.asm.org/content/90/14/6200.abstract
[size=1.2em]Monoclonal Antibodies to Different Components of the Human Cytomegalovirus (HCMV) Pentamer gH/gL/pUL128L and Trimer gH/gL/gO as well as Antibodies Elicited during Primary HCMV Infection Prevent Epithelial Cell Syncytium Formation
[size=1em]Giuseppe Gerna, Elena Percivalle, Laurent Perez, Antonio Lanzavecchia, and Daniele Lilleri
[size=1em]J. Virol. July 2016 90:6216-6223; Accepted manuscript posted online 27 April 2016, doi:10.1128/JVI.00121-16
http://jvi.asm.org/content/90/14/6216.abstract
[size=1.2em]Highly Pathogenic Avian Influenza H5N6 Viruses Exhibit Enhanced Affinity for Human Type Sialic Acid Receptor and In-Contact Transmission in Model Ferrets
[size=1em]Honglei Sun, Juan Pu, Yandi Wei, Yipeng Sun, Jiao Hu, Litao Liu, Guanlong Xu, Weihua Gao, Chong Li, Xuxiao Zhang, Yinhua Huang, Kin-Chow Chang, Xiufan Liu, and Jinhua Liu
[size=1em]J. Virol. July 2016 90:6235-6243; Accepted manuscript posted online 27 April 2016, doi:10.1128/JVI.00127-16
http://jvi.asm.org/content/90/14/6235.abstract
[size=1.2em]Biphasic CD8+ T-Cell Defense in Simian Immunodeficiency Virus Control by Acute-Phase Passive Neutralizing Antibody Immunization
[size=1em]Sumire Iseda, Naofumi Takahashi, Hugo Poplimont, Takushi Nomura, Sayuri Seki, Taku Nakane, Midori Nakamura, Shoi Shi, Hiroshi Ishii, Shota Furukawa, Shigeyoshi Harada, Taeko K. Naruse, Akinori Kimura, Tetsuro Matano, and Hiroyuki Yamamoto
[size=1em]J. Virol. July 2016 90:6276-6290; Accepted manuscript posted online 27 April 2016, doi:10.1128/JVI.00557-16
http://jvi.asm.org/content/90/14/6276.abstract
[size=1.2em]Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets
[size=1em]Benjamin A. Satterfield, Robert W. Cross, Karla A. Fenton, Viktoriya Borisevich, Krystle N. Agans, Daniel J. Deer, Jessica Graber, Christopher F. Basler, Thomas W. Geisbert, and Chad E. Mire
[size=1em]J. Virol. July 2016 90:6326-6343; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00215-16
http://jvi.asm.org/content/90/14/6326.abstract
[size=1.2em]The Foot-and-Mouth Disease Carrier State Divergence in Cattle
[size=1em]Carolina Stenfeldt, Michael Eschbaumer, Steven I. Rekant, Juan M. Pacheco, George R. Smoliga, Ethan J. Hartwig, Luis L. Rodriguez, and Jonathan Arzt
J. Virol. July 2016 90:6344-6364; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00388-16 [size=0.9em]OPEN ACCESS
http://jvi.asm.org/content/90/14/6344.abstract
[size=1.2em]CD69 Deficiency Enhances the Host Response to Vaccinia Virus Infection through Altered NK Cell Homeostasis
[size=1em]Laura Notario, Elisenda Alari-Pahissa, Antonio de Molina, and Pilar Lauzurica
[size=1em]J. Virol. July 2016 90:6464-6474; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00550-16
http://jvi.asm.org/content/90/14/6464.abstract
[size=1.2em]The Emerging Duck Flavivirus Is Not Pathogenic for Primates and Is Highly Sensitive to Mammalian Interferon Antiviral Signaling
[size=1em]Hong-Jiang Wang, Xiao-Feng Li, Long Liu, Yan-Peng Xu, Qing Ye, Yong-Qiang Deng, Xing-Yao Huang, Hui Zhao, E-De Qin, Pei-Yong Shi, George F. Gao, and Cheng-Feng Qin
[size=1em]J. Virol. July 2016 90:6538-6548; Accepted manuscript posted online 4 May 2016, doi:10.1128/JVI.00197-16
http://jvi.asm.org/content/90/14/6538.abstract
[size=1.2em]Both CD8+ and CD4+ T Cells Contribute to Corneal Clouding and Viral Clearance following Vaccinia Virus Infection in C57BL/6 Mice
[size=1em]I. V. Larsen, H. Clausius, A. W. Kolb, and C. R. Brandt
[size=1em]J. Virol. July 2016 90:6557-6572; Accepted manuscript posted online 11 May 2016, doi:10.1128/JVI.00570-16
http://jvi.asm.org/content/90/14/6557.abstract
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