洛克菲勒研究员Charles Rice荣获2015年科赫奖

Biodog

查尔斯·赖斯（Charles M. Rice），莫里斯R（Maurice R）和科琳娜P.格林伯格（Corinne P. Greenberg ）教授在病毒学领域中获得了2015年的罗伯特·科赫奖。Rice将分享由德国罗伯特·科赫基金会颁发€100,000的奖金，奖励他们在丙型肝炎病毒的开创性工作。科学家们将荣幸地为他们在11月正式颁奖典礼的成就。
罗伯特科赫基金会是总部设在德国柏林，一个非营利性组织，支持医学的进步，主要是在传染病领域，通过推进基础科学研究。罗伯特·科赫奖的同名，是现代细菌学的创始人，并赢得了1905年诺贝尔医学奖和生理学为他的研究在这门学科。从1891年直到他在1904年退休后，科赫是头研究所在柏林传染病。罗伯特·科赫奖每年都颁发，是德国最负盛名的科学奖项之一。
丙型肝炎病毒是慢性肝病和急性肝炎的主要原因，并且在世界范围内影响大约1.30至1.7亿人。Rice和Bartenschlager所做基础研究为新的治疗方法的发现奠定基础，这种治疗在大多数患者体内永消除了病毒。Rice的实验室在洛克菲勒病毒和传染病的实验室，首次获得了丙型肝炎病毒的分子单克隆，旨在通过研究病毒的复制和病毒与宿主细胞相互作用产生有效的疗法和疫苗。Rice和Bartenschlager二人的发现都被认为有助于理解病毒的生命周期，揭露有前途的抗病毒的目标，以及创建可重复的细胞培养系统对于可能也可用于药物筛选和检测基本研究。
Rice在1974获得美国加州大学戴维斯分校的学士学位，1981年在加利福尼亚技术研究所获得博士学位。先加入洛克菲勒，他是一名教师，在圣路易斯华盛顿大学任教15年。被认为是世界权威的病毒学家之一，Rice担任过美国国家科学院社会病毒学的的主席，是美国科学协会高级的研究员。 该公告标志着连续第二年洛克菲勒教员已经收到了罗伯特·科赫奖;去年的奖颁给了让 - 洛朗卡萨诺瓦为他的工作对理解宿主基因及其产物的传染病。拉尔夫斯坦曼是这个奖在1999年的第一个洛克菲勒收件人。【biodog翻译】

原文：Charles M. Rice, Maurice R. and Corinne P. Greenberg Professor in Virology, has been selected to receive the 2015 Robert Koch Award. Rice will share the €100,000 prize, awarded by the Robert Koch Foundation of Germany, with Ralf Bartenschlager from Heidelberg University for their groundbreaking work on the hepatitis C virus. The scientists will be honored for their achievements at a formal award ceremony in November.

The Robert Koch Foundation is a nonprofit organization based in Berlin, Germany, that supports medical advancement, primarily in the field of infectious disease, through the promotion of basic scientific research. Robert Koch, the award’s namesake, was the founder of modern bacteriology and won the 1905 Nobel Prize for Medicine and Physiology for his research in this discipline. From 1891 until his retirement in 1904, Koch was head of the Institute for Infectious Diseases in Berlin. The Robert Koch award is conferred annually and is one of Germany’s most prestigious scientific awards.

The hepatitis C virus is a major cause of chronic liver disease and acute hepatitis, and affects approximately 130 to 170 million people worldwide. The basic research discoveries made by Rice and Bartenschlager have laid the foundation for newly developed treatments that permanently eliminate the virus in the majority of treated patients. Rice’s lab at Rockefeller, the Laboratory of Virology and Infectious Disease, produced the first infectious molecular clone of the hepatitis C virus and aims to generate effective therapies and vaccines by investigating virus replication and virus-host cell interaction. Both Rice and Bartenschlager are credited with helping to understand the virus’ lifecycle, uncovering promising antiviral targets, and creating reproducible cell culture systems for basic studies that may also be used for drug screening and testing.

Rice earned his bachelor’s degree from University of California Davis in 1974 and his Ph.D. from the California Institute of Technology in 1981. Prior to joining Rockefeller, he was a faculty member at Washington University in St. Louis for 15 years. Considered one of the world’s leading virologists, Rice is a past president of the American Society for Virology, a Member of the National Academy of Sciences, and a fellow of the American Association for the Advancement of Science.

The announcement marks the second consecutive year that a Rockefeller faculty member has received the Robert Koch Award; last year’s award went to Jean-Laurent Casanova for his work on understanding host genes and their products in infectious diseases. Ralph Steinman was the first Rockefeller recipient of this prize in 1999.

链接：http://newswire.rockefeller.edu/ ... -robert-koch-award/

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