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【书名版次】： Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology)
1 m3 `5 H; C3 S' X; @% b【作 者】：Richard O. Snyder (Editor), Philippe Moullier (Editor)6 ?, L( q& p% }) L/ z' m
【出 版 社】: Humana Press; 2011 edition
! S" J0 |/ S" m8 Y$ T+ ~【出版日期】： (November 30, 2011) 5 D/ P# E4 w* D) E0 m' q; ]
0 f/ b G/ A" _* p【简 介】： Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.0 `) ~+ s; i+ t0 m
【目 录】： 8 n/ E+ t6 h7 r5 J# W4 d3 I
Hardcover: 475 pages" l* Y( E/ g' p8 ^8 m
Language: English
$ m7 S4 t/ y& R. m2 Q; pISBN-10: 1617793698
O9 `" m6 u+ E. f0 ]% I& bISBN-13: 978-16177936918 p4 X: N% r( i6 K
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发表于 2015-2-2 17:53:30
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发表于 2018-2-14 14:33:09
