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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology)
( j6 {2 O. S, ~, v+ O9 G$ F【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)
^" V5 u2 Q+ F8 F( d8 o' t【出 版 社】: Humana Press; 2011 edition1 }2 v7 E" x8 G" c
【出版日期】: (November 30, 2011) : s7 C# e2 V o) }7 u
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【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
- w, |: D; q9 \! j, ?【目 录】:
3 _8 h. D7 E, C$ x1 `4 A' hHardcover: 475 pages8 P- a5 C4 r, }$ ^
Language: English
$ p' R5 J! M3 ^# i; j: tISBN-10: 16177936983 j8 v. x3 M6 W5 t
ISBN-13: 978-1617793691" |9 T8 x, Y# m! R: P+ r
下载地址:$ }: H( X* p) p7 @2 l. ]) t: D
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