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3 `, t" a6 z6 {# n, ~Viral Pathogenesis and Immunity 2nd 名著再版
6 V8 S( ~) M$ C5 T0 s【书名版次】：Viral Pathogenesis and Immunity Second（Second edition）
* ^0 s* A0 Y& ?9 N- y( n; T3 x, i【作 者】：Neal Nathanson
% V9 s+ @# g( w6 O& `【出 版 社】: Academic Press# n6 Q' o/ T8 s4 N4 c4 n
【简 介】：/ ^- S1 n6 u( c$ B
名著再版 - l1 O1 p0 a, h: I1 J- v4 w
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This book is the direct offspring of Viral Pathogenesis,% b* t/ J$ X( a Y( g$ E/ w
published in 1997. Having read several drafts of all the0 C0 n$ B; o: q
chapters in Viral Pathogenesis, it was clear that the large
- N7 e! t; D# Y+ m' s% I2 Ibook contained a wealth of information, but that it was1 T& ?6 M4 w$ I9 _
unsuited for readers who desired an introduction to the8 K1 Y+ ~# W7 z5 s
topic. From that observation sprang the plan for a short. e; q; ] x& G" } `$ W8 D
version that could be used as an introductory text or for" J; I. B0 l/ |: N% T- x# f
self-education.
, [/ H# V4 D0 B: q4 t3 YAn introductory text clearly benefits from the9 ]9 @4 j3 D0 u) N. K' O( `7 N' r
coherence provided by a single author, but suffers from/ m4 u- D7 z. ^/ [! z
the finite expertise of any single researcher. Therefore, a3 e3 c( r e/ _0 n
compromise was devised, in which each chapter was coauthored
9 _! G4 X2 E0 T! f# ?0 Iby an expert in the specific area under consideration.! g2 r0 X- ~; Z. F
This strategy was facilitated by the successful. ]( u+ x' k1 E+ j3 {
collaborations that had been developed during the
: t. J0 w- E& b8 b$ Lpreparation of Viral Pathogenesis. The text includes: F( Z* u3 y* {/ t+ g& t- B
references published through to June, 2006.
* j' D2 U/ C; ] H7 T) ~- WI would like to acknowledge the contributions of the/ ]+ C8 x3 K: [! x5 g
co-authors. Their advice and expertise has been essential+ X B- T$ x" `) {' r3 y
to the planning and execution of this undertaking and it% C5 o% D6 G3 _3 s. w2 a
has been a continual pleasure to work with them. They F/ N" @' |8 b$ L
have provided extremely cogent suggestions that have( t! z. n' H% t8 N( @2 O' r/ T3 h
given the book an enhanced level of authority that could) u* f; X0 B1 J1 k0 _& A5 N6 D2 ?
not otherwise have been achieved.
?- L5 W2 |) O3 e4 @, a5 NLisa Tickner and the staff at Academic Press,% A+ k; _) K! o. h" u+ r
London, have been an ongoing source of support both
6 x3 X& y- A. B5 T) T) `" L) ubecause of their enthusiasm for this book and their
5 ~5 D, l: q) [ Z! u' N6 whighly professional expertise in all phases of the project.
' j) l0 a* D+ OWendy Jackelow provided the outstanding illustrations
7 q$ i8 ]2 U! G6 y& Erendered from a wide variety of often primitive sketches.1 L }+ ]& z, V: ~* G) X
Neal Nathanson) @- s% l: W" a% S# E
Philadelphia% z" G7 @, y* F- z8 m
【出版日期】：20074 j% @2 z/ d% z! t
【Contents】:
5 C, i# o ]& ?3 u0 b, T
8 r3 w6 @4 W6 g7 Y% uList of Co-authors vii
. ]# j, b( Q. b, V v+ lPreface ix
( p) O: M: j2 d5 ]2 k( l; M) y; L1 IIntroduction xi7 r. l" \6 L- g2 Z6 v
Part I Essentials of Viral Pathogenesis 1
% ?) F6 R1 N$ b! i# U1 y# I1 Historical Roots 3: F5 p: P9 v) m9 h- S3 x2 \# _
Neal Nathanson and Frederick A.Murphy A1 T- M, W+ {4 L1 J& F" k
2 The Sequential Steps in Viral Infection 14
& S! `; X- S: p$ oNeal Nathanson and Frederick A.Murphy
/ ^$ y6 w: ~6 `0 @$ o) z. o9 `& p3 Cellular Receptors and Viral Tropism 278 b( |3 u: {- R
Neal Nathanson and Kathryn V. Holmes9 N" u ~+ ~& L6 X/ G! h
4 Virus–Cell Interactions 41
( [: ~8 \+ n N& GNeal Nathanson and Diane E. Griffin! W+ m0 i2 w- f/ G' S* i
Part II Host Responses to Viral Infection 57
( U4 F/ T0 v, z' `. y* X z5 Innate Immunity 59
4 Z9 S' x! T9 N) }' `$ r8 a/ BNeal Nathanson and Christine A. Biron
1 `* \8 Y/ Q/ Y t1 u4 w8 ~) z6 Immune Responses to Viral Infection 72* T/ Z# J, {1 Q3 l
Neal Nathanson and Rafi Ahmed
7 b" _" L2 v5 E' t7 Virus-Induced Immunopathology 88* P! R) f+ v' j2 K( i0 `4 H u' [
Neal Nathanson and Rafi Ahmed; G2 e; r) i7 V3 M
8 Virus-Induced Immunosuppression 99
6 @1 G0 `+ g5 e8 @- qNeal Nathanson and Diane E. Griffin) n+ c9 t Z. E2 ~7 Q
Part III Virus–Host Interactions 111" N1 N8 X5 |* L% A
9 Viral Virulence 113
" ?1 W+ d8 w* C8 t' |" ~Neal Nathanson and Francisco
; f' R% ]: ~, [* j9 ]Gonzalez-Scarano$ P6 M, B! e% p. ^' @# Z0 R5 ~& S4 H
10 Viral Persistence 130. }0 D, H# h$ {8 s& [6 P
Neal Nathanson and Francisco
) h9 @1 O$ i- r/ `5 ^1 u0 nGonzalez-Scarano2 Q. V$ Z/ H6 s6 p
11 Viral Oncogenesis: Retroviruses 146
0 e! F3 l2 N% R0 ]Neal Nathanson and Harriet L. Robinson
. U+ a0 L1 t$ p) q! z/ m* k) B12 Viral Oncogenesis: DNA Viruses 158
; c, g. c, d7 w6 r! `: l9 [Neal Nathanson and Erle S. Robertson
' N8 e3 I" V0 E' _2 q( w13 Host Susceptibility to Viral Diseases 174! P9 ^9 x7 z. ^! r; S
Neal Nathanson and Margo A. Brinton
$ _* Q& ]! @* k1 r$ q5 J14 HIV, SIV and the Pathogenesis of AIDS 1859 P( K0 N8 x h ^6 _& k& r
Neal Nathanson and Julie Overbaugh+ F9 k0 M# ^' V9 ~2 o# T
Part IV Ecology and Control of Viral 2014 S; ~7 X: V# y/ v
Infections
- _( {* b3 h& v# u2 m, ?8 z2 W% y15 Emerging Viral Diseases 203& f& a" H" F% R, X. M
Neal Nathanson and Frederick A.Murphy3 ]. K% I9 [' j2 V; r1 I0 ^
16 Antiviral Therapy 221% l: S6 F, m1 m7 c
Neal Nathanson and Douglas D. Richman* g: D$ e* [& h" S2 b
17 Viral Vaccines 234/ j: ]0 M" D/ @$ C f
Neal Nathanson and Harriet L. Robinson
0 [% q2 c6 z$ L4 M; J$ FGlossary and Abbreviations 253, t2 r6 Q$ z9 Q# p4 `! S
Index 259; R. d. @/ y7 O- A% H! C% G
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