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Viral Pathogenesis and Immunity 2nd 名著再版( }+ y+ x2 F6 T& F7 y
【书名版次】：Viral Pathogenesis and Immunity Second（Second edition）
& Z& b+ H: D) L【作 者】：Neal Nathanson9 s' P/ a6 o1 {( E3 Z- V G+ o
【出 版 社】: Academic Press0 l- E S5 L% w9 Y; Y
【简 介】：
) C+ S$ Y" f3 L1 g% D9 [ 名著再版
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2 K- W, I3 l6 N7 B7 R I8 h This book is the direct offspring of Viral Pathogenesis,; Z! f& C0 E' T
published in 1997. Having read several drafts of all the
; |: m7 _( n6 N+ M9 o' i* @& Ichapters in Viral Pathogenesis, it was clear that the large
" @+ @8 b! q( Q$ wbook contained a wealth of information, but that it was
8 R$ C* w# l7 d) ^7 g3 I' Vunsuited for readers who desired an introduction to the3 O X; j! z- C* v9 X: k& @. ^ k# Y' c
topic. From that observation sprang the plan for a short" G9 n6 n# L- S7 M
version that could be used as an introductory text or for
* {& R+ k2 E6 @$ f9 G3 Sself-education.
! Q& u% f, N3 }% p3 v) h; TAn introductory text clearly benefits from the7 _+ \/ T: ?/ Y; C' {9 e
coherence provided by a single author, but suffers from
2 G& ?: v$ U( {( uthe finite expertise of any single researcher. Therefore, a
5 m9 G" ^# f1 I( ncompromise was devised, in which each chapter was coauthored
$ Q' b# f# d# j" b% K" [by an expert in the specific area under consideration.
7 f) s# t* W8 f7 h. yThis strategy was facilitated by the successful" r5 Y: N- p( V8 W2 V6 L
collaborations that had been developed during the5 m2 M* j* j- k- k
preparation of Viral Pathogenesis. The text includes/ T7 \& n, C* `' N
references published through to June, 2006.
; M* s8 c! S4 |4 w" A- zI would like to acknowledge the contributions of the
3 n G0 j H0 x7 Z! X% P$ u# e% fco-authors. Their advice and expertise has been essential
- S$ a, }% V# Z, n* qto the planning and execution of this undertaking and it# `' V& X, r8 p7 S8 @$ Y
has been a continual pleasure to work with them. They5 |( T3 E( Q2 v4 X
have provided extremely cogent suggestions that have8 F4 e. l1 t* G6 H" S1 I
given the book an enhanced level of authority that could
+ l" _- f- k' S, E1 U. {not otherwise have been achieved.
! G4 U; ?; V/ |. c3 b+ F& ELisa Tickner and the staff at Academic Press,
+ q* S0 o7 J% p8 Q4 a2 A7 uLondon, have been an ongoing source of support both
4 P/ d8 ^4 M% M4 O4 a2 ^because of their enthusiasm for this book and their, Z( d4 H& J8 y
highly professional expertise in all phases of the project.
; p- u% h; _& z7 j& nWendy Jackelow provided the outstanding illustrations% n. ]4 R, p0 c0 A, C
rendered from a wide variety of often primitive sketches.
5 f7 L! ?# J lNeal Nathanson
( E" @* g) U1 C6 p' V Y q# j! @4 LPhiladelphia' P8 y$ B0 B% a! I1 Q4 V( |8 p
【出版日期】：2007
8 J7 R$ b9 _/ _/ `3 j【Contents】:
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List of Co-authors vii* b% k( l% Y# R' U% o) O
Preface ix7 p. @+ o) \. Y5 |" _ C5 c; i' a
Introduction xi
) X. g: D; c2 i; ]. _! @Part I Essentials of Viral Pathogenesis 1
$ S/ X* \& y W4 f' V% S/ K1 Historical Roots 3
: C4 c K4 K) B+ c3 x$ uNeal Nathanson and Frederick A.Murphy% _2 P' h; G: }, H. ^4 U' {8 a. S2 G
2 The Sequential Steps in Viral Infection 14/ x5 ~# B+ s; n. K) l( |
Neal Nathanson and Frederick A.Murphy1 m, n1 M, c7 E* K8 J" x, W; n
3 Cellular Receptors and Viral Tropism 27- o* v& i* H; k7 \6 M5 H
Neal Nathanson and Kathryn V. Holmes
8 ]$ K4 k% b+ D* ^9 n) e4 Virus–Cell Interactions 41
# ~/ e! f. Y& _Neal Nathanson and Diane E. Griffin( ~# e8 _) }/ y
Part II Host Responses to Viral Infection 57
6 D3 D$ a1 r+ `: t/ ^. o% y5 Innate Immunity 59 t5 y q- W2 D0 r' B
Neal Nathanson and Christine A. Biron
, d" s- H4 W' k7 l) V6 Immune Responses to Viral Infection 72
8 l8 [" O9 q. M, S. I: T, h' ]' |Neal Nathanson and Rafi Ahmed
t3 k' f0 B" z- \7 Virus-Induced Immunopathology 88
! G$ M% N& p: k! G' |& E. eNeal Nathanson and Rafi Ahmed- N% c) f" s" g1 W# X! r8 _
8 Virus-Induced Immunosuppression 99
/ l; ~* r, A/ uNeal Nathanson and Diane E. Griffin
( E3 D! }4 o9 `Part III Virus–Host Interactions 111
* P! T, t2 g. O* w. J! ^9 Viral Virulence 113% ~& q Y2 G7 f* H: y+ a
Neal Nathanson and Francisco
c8 V; `2 E2 \1 `8 u, S3 I7 d" lGonzalez-Scarano
: _, P0 m6 D0 E6 @& I10 Viral Persistence 130) q4 q6 z0 s+ H; Q
Neal Nathanson and Francisco" }$ \% P" N0 \( v7 ?' H
Gonzalez-Scarano
0 K9 @" m1 `4 v. H& x* x. m11 Viral Oncogenesis: Retroviruses 146# J- N- c4 ~) t x3 C
Neal Nathanson and Harriet L. Robinson
) m3 x$ O! P4 R7 Z# P12 Viral Oncogenesis: DNA Viruses 158
a* K+ l/ _3 I H; i; N, O. SNeal Nathanson and Erle S. Robertson% g% t z6 R8 @/ P# ]
13 Host Susceptibility to Viral Diseases 174
* Y3 H9 l0 h. j3 J4 jNeal Nathanson and Margo A. Brinton: P% ^3 H& }- z
14 HIV, SIV and the Pathogenesis of AIDS 1859 m; l" y1 |6 Y9 A3 F' `) m, [
Neal Nathanson and Julie Overbaugh3 u7 `$ G* S4 \; q; `. j% D
Part IV Ecology and Control of Viral 201" ]0 y+ d2 V. {
Infections
! @0 v2 f( L9 ~15 Emerging Viral Diseases 203
8 y& s* l! J. h9 H# K! i# BNeal Nathanson and Frederick A.Murphy: s- Z/ P1 F% d( }
16 Antiviral Therapy 2214 y9 ?) g$ J+ m9 K$ V, d
Neal Nathanson and Douglas D. Richman
" ^9 M5 X z* q17 Viral Vaccines 234
& z( o* V v9 {Neal Nathanson and Harriet L. Robinson
. q& k9 j: g4 W) C+ O5 }Glossary and Abbreviations 253
& y* H! b1 @, N1 i: j4 }" G0 `. R) a5 `Index 259
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