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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology)
# l _5 k3 s; G; C. I# X% r【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)
; \& w/ [9 s% k- @6 Z, V8 R【出 版 社】: Humana Press; 2011 edition1 t) N) x, R2 G* Z$ `# E- G' q
【出版日期】: (November 30, 2011) 1 e% R$ r `5 q: p
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【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.2 e. K2 v3 z+ z. ?. w' _2 u! S
【目 录】:
: l W( J2 {( G& aHardcover: 475 pages
% J1 U g" R4 t' @7 @ Language: English
( |) U1 G6 l' {ISBN-10: 1617793698
+ W* i! ^- i" U# S' I7 C+ I0 sISBN-13: 978-1617793691) t# U5 _6 C/ g% r+ u9 ]; ?; a
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