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GuoJutao & GuoHaitao,宾夕法尼亚——HBV相关实验室及人物介绍

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发表于 2016-5-10 02:36:03 | 只看该作者 回帖奖励 |倒序浏览 |阅读模式
GuoJutao & GuoHaitao,宾夕法尼亚——HBV相关实验室及人物介绍系列

GuoJutao & GuoHaitao,德雷克塞尔大学医学院,宾夕法尼亚
Drexel University College of Medicine, Doylestown,宾夕法尼亚
专注研究乙肝最重要的cccDNA

Block, T. M. and J. T. Guo (2016). "The Covalently Closed Circular Form of Hepatitis B Virus Genome: Is There Now an  End in "Site"?" Gastroenterology 150(1): 34-6.
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Guo, J. T. and H. Guo (2015). "Metabolism and function of hepatitis B virus cccDNA: Implications for the development of cccDNA-targeting antiviral therapeutics." Antiviral Res 122: 91-100.
Liang, T. J. and T. M. Block, et al. (2015). "Present and future therapies of hepatitis B: From discovery to cure." Hepatology 62(6): 1893-908.
Yan, R. and X. Zhao, et al. (2015). "The Interferon-Inducible Protein Tetherin Inhibits Hepatitis B Virus Virion Secretion." J Virol 89(18): 9200-12.
Chang, J. and J. T. Guo (2015). "Treatment of chronic hepatitis B with pattern recognition receptor agonists: Current status and potential for a cure." Antiviral Res 121: 152-9.
Cui, X. and J. T. Guo, et al. (2015). "Hepatitis B Virus Covalently Closed Circular DNA Formation in Immortalized Mouse  Hepatocytes Associated with Nucleocapsid Destabilization." J Virol 89(17): 9021-8.
He, W. and B. Ren, et al. (2015). "Hepatitis D Virus Infection of Mice Expressing Human Sodium Taurocholate Co-transporting Polypeptide." PLoS Pathog 11(4): e1004840.
Guo, F. and Y. Han, et al. (2015). "STING agonists induce an innate antiviral immune response against hepatitis B virus." Antimicrob Agents Chemother 59(2): 1273-81.
Jain, S. and T. T. Chang, et al. (2015). "Comprehensive DNA methylation analysis of hepatitis B virus genome in infected liver tissues." Sci Rep 5: 10478.
Chang, J. and F. Guo, et al. (2014). "Therapeutic strategies for a functional cure of chronic hepatitis B virus infection." Acta Pharm Sin B 4(4): 248-57.
Zhang, Y. and R. Mao, et al. (2014). "Transcription of hepatitis B virus covalently closed circular DNA is regulated by CpG methylation during chronic infection." PLoS One 9(10): e110442.
Zhang, S. and J. T. Guo, et al. (2013). "Identification and characterization of multiple TRIM proteins that inhibit hepatitis B virus transcription." PLoS One 8(8): e70001.
Mao, R. and H. Nie, et al. (2013). "Inhibition of hepatitis B virus replication by the host zinc finger antiviral protein." PLoS Pathog 9(7): e1003494.
Cai, D. and H. Nie, et al. (2013). "A southern blot assay for detection of hepatitis B virus covalently closed circular DNA from cell cultures." Methods Mol Biol 1030: 151-61.
Campagna, M. R. and F. Liu, et al. (2013). "Sulfamoylbenzamide derivatives inhibit the assembly of hepatitis B virus nucleocapsids." J Virol 87(12): 6931-42.
Block, T. M. and R. Gish, et al. (2013). "Chronic hepatitis B: what should be the goal for new therapies?" Antiviral Res 98(1): 27-34.
Chang, J. and T. M. Block, et al. (2012). "The innate immune response to hepatitis B virus infection: implications for pathogenesis and therapy." Antiviral Res 96(3): 405-13.
Cai, D. and C. Mills, et al. (2012). "Identification of disubstituted sulfonamide compounds as specific inhibitors of hepatitis B virus covalently closed circular DNA formation." Antimicrob Agents Chemother 56(8): 4277-88.
Qu, X. and X. Pan, et al. (2011). "Inhibitors of endoplasmic reticulum alpha-glucosidases potently suppress hepatitis C virus virion assembly and release." Antimicrob Agents Chemother 55(3): 1036-44.
Mao, R. and J. Zhang, et al. (2011). "Indoleamine 2,3-dioxygenase mediates the antiviral effect of gamma interferon against hepatitis B virus in human hepatocyte-derived cells." J Virol 85(2): 1048-57.
Xu, C. and H. Guo, et al. (2010). "Interferons accelerate decay of replication-competent nucleocapsids of hepatitis  B virus." J Virol 84(18): 9332-40.
Guo, H. and D. Jiang, et al. (2009). "Activation of pattern recognition receptor-mediated innate immunity inhibits the  replication of hepatitis B virus in human hepatocyte-derived cells." J Virol 83(2): 847-58.
Chang, J. and J. T. Guo, et al. (2008). "Liver-specific microRNA miR-122 enhances the replication of hepatitis C virus in  nonhepatic cells." J Virol 82(16): 8215-23.
Jiang, D. and H. Guo, et al. (2008). "Identification of three interferon-inducible cellular enzymes that inhibit the replication of hepatitis C virus." J Virol 82(4): 1665-78.
Block, T. M. and H. Guo, et al. (2007). "Molecular virology of hepatitis B virus for clinicians." Clin Liver Dis 11(4): 685-706, vii.
Dougherty, A. M. and H. Guo, et al. (2007). "A substituted tetrahydro-tetrazolo-pyrimidine is a specific and novel inhibitor of hepatitis B virus surface antigen secretion." Antimicrob Agents Chemother 51(12): 4427-37.
Guo, H. and D. Jiang, et al. (2007). "Characterization of the intracellular deproteinized relaxed circular DNA of hepatitis B virus: an intermediate of covalently closed circular DNA formation." J Virol 81(22): 12472-84.
Guo, H. and T. Zhou, et al. (2007). "Regulation of hepatitis B virus replication by the phosphatidylinositol 3-kinase-akt signal transduction pathway." J Virol 81(18): 10072-80.
Zhou, T. and H. Guo, et al. (2006). "Hepatitis B virus e antigen production is dependent upon covalently closed circular (ccc) DNA in HepAD38 cell cultures and may serve as a cccDNA surrogate in antiviral screening assays." Antiviral Res 72(2): 116-24.
Guo, J. T. and J. A. Sohn, et al. (2004). "Mechanism of the interferon alpha response against hepatitis C virus replicons." Virology 325(1): 71-81.
Guo, J. T. and Q. Zhu, et al. (2003). "Cytopathic and noncytopathic interferon responses in cells expressing hepatitis C virus subgenomic replicons." J Virol 77(20): 10769-79.
Zhu, Q. and J. T. Guo, et al. (2003). "Replication of hepatitis C virus subgenomes in nonhepatic epithelial and mouse hepatoma cells." J Virol 77(17): 9204-10.
Guo, J. T. and M. Pryce, et al. (2003). "Conditional replication of duck hepatitis B virus in hepatoma cells." J Virol 77(3): 1885-93.
Guo, J. T. and V. V. Bichko, et al. (2001). "Effect of alpha interferon on the hepatitis C virus replicon." J Virol 75(18): 8516-23.
Zhou, T. and J. T. Guo, et al. (2000). "Combination therapy with lamivudine and adenovirus causes transient suppression of chronic woodchuck hepatitis virus infections." J Virol 74(24): 11754-63.
Ladner, S. K. and M. J. Otto, et al. (1997). "Inducible expression of human hepatitis B virus (HBV) in stably transfected hepatoblastoma cells: a novel system for screening potential inhibitors of HBV replication." Antimicrob Agents Chemother 41(8): 1715-20.
Guo, J. T. and J. C. Pugh (1997). "Monoclonal antibodies to a 55-kilodalton protein present in duck liver inhibit infection of primary duck hepatocytes with duck hepatitis B virus." J Virol 71(6): 4829-31.
Guo, J. T. and J. C. Pugh (1997). "Topology of the large envelope protein of duck hepatitis B virus suggests a mechanism for membrane translocation during particle morphogenesis." J Virol 71(2): 1107-14.
Guo, J. T. and H. S. Chen, et al. (1992). "[Uses of duck hepatitis B virus polymerase and reverse transcriptase in the evaluation of anti-hepatitis B virus drugs]." Zhongguo Zhong Xi Yi Jie He Za Zhi 12(8): 480-2, 454.
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